Women are more likely than men to have morbidity and death from heart failure, and they often experience it later in life. Women have heart failure more frequently than men do, and at least half of these instances are heart failure with an intact ejection fraction. Women are more symptomatic and have a worse prognosis than men when they suffer heart failure and a low left ventricular ejection fraction. Men and women receive the same overall recommendations for medical therapy that follow established guidelines.